Editorial

Different risks, different responses: COVID-19 vaccination in immunocompromised patients

Immunocompromised individuals, including those with haematological malignancies, autoimmune diseases, or solid organ dysfunction, as well as those receiving long-term immunosuppressive therapy, bear a disproportionate...

Beyond LDL-C: Desialylated LDL as a refined marker of coronary atherosclerosis severity

The core role of low-density lipoprotein cholesterol (LDL-C) in atherosclerosis is well validated. However, the "LDL hypothesis" has evolved over the last 4 decades;...

RDW-to-albumin ratio correlates with serum neurofilament light chain

Blood-based biomarkers are reshaping the study of neurological disease. Among these, neurofilament light chain (NfL) has emerged as one of the most sensitive peripheral...

Grip strength, sleep status and depression

Frailty screening in community-dwelling older adults offers an opportunity for early identification to mitigate downstream disease burden. Hand grip strength as a simple, reliable...

Rethinking risk: Mental health and resilience of migrant workers and migrant domestic workers in...

Over the past 5 years, there has been growing attention to the health and well-being of international migrant workers (MWs) in Singapore, particularly low-...

Screening for tuberculosis in chronic kidney disease patients

Tuberculosis (TB) is the leading infectious cause of morbidity and mortality globally.1 Singapore is considered a lower-moderate incidence country (estimated TB incidence at 10–49...

Beyond tumour necrosis factor inhibition: Revisiting latent tuberculosis infection testing in rheumatology

Dear Editor, Tuberculosis (TB) remains a major public health challenge in Asia and continues to require consideration during clinical decision-making in Singapore. Although the incidence...

Towards a holistic and improved clinical management of menopause

As life expectancy increases, women may spend a significant number of years that can amount to almost a third of their life in the...

Quality in gastroscopy: Consensus statements from the Gastroenterological Society of Singapore

The upper gastrointestinal (UGI) endoscope is often the first scope that a novice endoscopist handles and learns to use. However, being able to navigate...

Leveraging real-world data to develop long-term follow-up programmes for childhood cancer survivors

In this issue of the Annals, Lam Shang Leen et al. comprehensively audited the late effects experienced by 485 childhood cancer survivors who visited...
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