Volume 52, Number 8
August 2023

High exposure to heavy metals such as cadmium, lead, arsenic and mercury can cause nephrotoxicity.

A study highlights the protective effects of micronutrients against chronic kidney disease (CKD). While high blood levels of heavy metals increased the risk of CKD, elevated plasma selenium and serum zinc levels may interact with low-toxicity heavy metals to reduce CKD risk.

Illustration by Ngiam Li Yi

Micronutrients and kidney health

Chronic kidney disease (CKD) is a structural and functional disorder of the kidney caused by many diseases, such as diabetes, hypertension and glomerular disease.1...

Impact of pre-existing depression on severe COVID-19 outcomes

The outbreak of the COVID-19 virus in 2019 had rapidly developed into a global pandemic, causing more than 6.8 million deaths and impacting the...

Association of anticoagulation use during continuous kidney replacement therapy and 90-day outcomes: A multicentre study

Acute kidney injury (AKI) affects 21.6% of critically ill adult patients,1 with 5–7% requiring kidney replacement therapy (KRT).2 AKI carries significant prognostic and socioeconomic...

Plasma selenium and zinc alter associations between nephrotoxic metals and chronic kidney disease: Results from NHANES database 2011–2018

Chronic kidney disease (CKD) is a clinical condition comprising persistent changes in kidney function or structure, or both. It is characterised by irreversible and...

Poorer outcomes following COVID-19 infection for patients with depression: A cohort analysis in South Korea

In the early days of the pandemic, a major public health focus was to slow the spread of COVID-19. Therefore, the emphasis was on...


Review on Epidemic of Obesity

Rationale for Redefining Obesity in Asians