Volume 51, Number 1
January 2022

The Academy of Medicine, Singapore recently appointed an expert workgroup comprising gastroenterologists, general surgeons and anaesthesiologists to develop guidelines on the use of sedation during gastrointestinal (GI) endoscopy. The recommendations serve to guide clinical practice during sedation for GI endoscopy by non-anaesthesiologists in the hospital setting.

Proton-pump inhibitors (PPIs) are effective treatment for upper GI pathologies but their indiscriminate use could result in potential harms. A Singapore study had implemented a series of deprescribing interventions to curb PPI overutilisation, with findings supporting the safety of cautious deprescribing.

Ensuring safe sedation during gastroendoscopy

Gastrointestinal (GI) endoscopy started in Singapore in 1968 with diagnostic endoscopic gastric examination, using flexible fibre-optics GI endoscopy. Fibre-optic flexible sigmoidoscopy and colonoscopy were...

Proton pump inhibitors: When is it too much of a good thing?

The popularity of proton pump inhibitors (PPIs) among both prescribers and patients may be ascribed to their relative low cost, efficacy and safety profile....

Coagulopathy related to trauma: Is it time for a goal-directed approach?

Trauma represents a leading cause of death globally, and post-traumatic haemorrhage accounts for 40% of early mortality in spite of recent improvements in modern...

The impact of deprescribing interventions on oral proton pump inhibitor utilisation in a Singapore tertiary hospital: A quality improvement initiative

The established efficacy of proton pump inhibitors (PPIs) in the treatment of upper gastrointestinal (GI) disorders, coupled with their perceived safety, have led to...

Novel transdermal device for delivery of triamcinolone for nail psoriasis treatment

Psoriasis is a chronic immune mediated inflammatory skin condition that affects about 2–4% of the Western populations, with rising incidence over the years.1,2 The...


Review on Epidemic of Obesity

Rationale for Redefining Obesity in Asians


Challenges to smoking cessation in patients with substance use disorders

Hantavirus haemorrhagic fever and renal syndrome, caused by the Hantaan virus...