Volume 54, Number 1
January 2025

A clinical audit of 1766 paediatric intensive care unit admissions discusses the large gap between eligible and actual organ donation by non-survivors.

Illustration by Maria De-Castro

Epidemiology of paediatric intensive care unit admissions, deaths and organ donation candidacy: A single-centre audit

With advancements in medical care, mortality rates in critically ill patients have decreased substantially.1,2 Contemporary studies from developed countries report paediatric intensive care mortality rates of 2–3%3,4 in 2014 to 2019, whereas mortality in developing countries can be as high as 50%5 as of 2024, indicating large disparities in...

Navigating the evolving landscape in the prescribing of medications for insomnia in Singapore: Principles and considerations from a psychiatrist’s perspective

The risks of prescribing benzodiazepines and Z-drugs for insomnia are well recognised by regulators, where the prescribing of such medications in contravention of guidelines has been the subject of regulatory action.1,2 Medical practitioners involved in the prescription of such medications need to grapple with complex clinical, legal, ethical and...

Improving school teachers’ self-efficacy and knowledge on food allergy and management of anaphylaxis using a virtual multidisciplinary workshop

Dear Editor, Children with food allergies are at risk of inadvertent allergic reactions that range from mild to potentially life-threatening anaphylaxis, even with appropriate dietary avoidance.1 This risk is often increased in community settings such as schools via accidental exposure to allergens during learning activities or meal times. A quarter...

Interventional radiology placement of totally implantable venous access devices in oncology practice

In November 1929, Werner Forssmann, a German surgical resident, attempted the first documented central venous catheter with a 35 cm-long catheter via his left antecubital vein.1 Although revolutionary for his time, this innovation encountered significant opposition, and he was expelled from his training programme for this unauthorised experimentation. Despite...

Long-term survival and clinical implications of allogeneic stem cell transplantation in relapse/refractory lymphoma: A 20-year Singapore experience

Over the past few decades, a wide array of novel therapies has become available for the treatment of relapsed/refractory (R/R) lymphoma. Despite these advancements, outcomes and the durability of disease control remain poor for many patients. While autologous hematopoietic stem cell transplantation (auto-HSCT) may be appropriate for some lymphoma...

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