Volume 52, Number 11
November 2023

Gram-negative bacteria are found to be frequently multidrug-resistant and the predominant cause of infections among preterm infants in the neonatal intensive care unit.

Read Burden of antibiotic resistance in infections among very-low-birthweight infants in Singapore, published in the November issue of the Annals.

Illustration by Nata Blackthorn

Paradigm shifts in haemophilia A therapy with emicizumab prophylaxis in Asia

Over the past decade, the development of emicizumab, the first-in-class factor VIII (FVIII)-mimetic monoclonal antibody bispecific to activated factor IX and factor X, has...

Improving management of AL amyloidosis

In this issue of the Annals, Tan et al. on behalf of Singapore Myeloma Study Group presented the consensus guidelines on light chain (AL)...

Burden of antibiotic resistance in infections among very-low-birthweight infants in Singapore

Recent reports have described an increased predominance of Gram-negative organisms (Escherichia coli, Klebsiella species ) among invasive bacterial infections in early- and late-onset neonatal...

Risk of dementia in the elderly with non-alcoholic fatty liver disease: A nested case-control study in the Republic of Korea

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease affecting about 25% of the general population.1,2 NAFLD has a broad disease...

Real-world data on the use of emicizumab in patients with haemophilia A with and without inhibitors in Singapore

Haemophilia A is an X-linked hereditary bleeding disorder caused by pathogenic genetic variants, which results in a deficiency of factor VIII (FVIII).1 The mainstay...


Review on Epidemic of Obesity

Rationale for Redefining Obesity in Asians