Suicide, the deliberate act to end one’s life, has been described as the “result of fractures with oneself”.1 It could manifest as a direct consequence of psychiatric illness—such as severe depression with an overwhelming sense of hopelessness—or a compliant act under the influence of a command hallucination in psychotic...

Glaucoma is one of the world’s leading causes of irreversible blindness, with certain types of glaucoma such as angle-closure glaucoma being more prevalent in East Asia.1 The global prevalence is currently estimated to be 3.54% in those aged 40-80 years old.2 People affected by glaucoma in 2013 was estimated...

For many years, the clinical dogma of early goal-directed therapy (EGDT) with fluid resuscitation was one of the cornerstones of treatment in sepsis.1,2 Surviving Sepsis Campaign guidelines recommended fluid resuscitation to restore mean circulating filling pressure guided by bedside parameters for patients with sepsis.3 However, recent studies have challenged...

In subcutaneous panniculitis-like T-cell lymphoma (SPTL), infiltration of subcutaneous tissue by pleomorphic T-cells and benign macrophages is seen in skin nodules that mimic lobular panniculitis. SPTL affects young patients and about 20% develop haemophagocytic syndrome (HPS) which worsens survival significantly.1,2 We describe a case of aggressive SPTL in a...

Dear Editor, Psoriasis is a common chronic inflammatory skin disease. On the other hand, autoimmune bullous diseases (AIBD) are less prevalent. Several case reports and studies have documented AIBD in patients with psoriasis.1,2 However, their causative factors are unclear. It has been hypothesised that certain antipsoriatic treatments such as ultraviolet...