Cerebral palsy (CP) is one of the most common and severe disabilities in childhood. The Cerebral Palsy Registry in Singapore was established in 2017 to describe the clinical characteristics and functional outcomes of CP in Singapore. It found that pre/perinatally acquired CP accounted for a majority of cases, with prematurity as the main risk factor. Optimisation of pre- and perinatal care to prevent and manage prematurity, together with early diagnosis and intervention, is important to reduce the incidence, severity and lifelong burden of CP in Singapore.