Volume 54, Number 3
Research explores the latest advanced role, mechanism, treatment and safety of hydroxychloroquine (HCQ) in rheumatic diseases during pregnancy and application prospects of HCQ in preeclampsia.
Illustration by Maria De-Castro
Editorial
Strengthening HRQOL Assessment in Singapore: Updated Norms for EQ-5D-5L and EORTC QLQ-C30
Health-related quality of life (HRQOL) is increasingly used as an important indicator of health outcomes for measuring the impact of illness and treatment among individuals with mental or physical conditions. The EuroQol 5-dimension (EQ-5D) questionnaire is one of the most widely used generic measures for HRQOL and estimating the...
Editorial
Enhancing HIV pre-exposure prophylaxis using telehealth: Insights from the iPARTY study
Human immunodeficiency virus (HIV) infections are increasing globally despite significant advancements in preventive and treatment programmes.1 This alarming trend is particularly pronounced within high-risk populations, especially among young men who have sex with men (YMSM). Given these rising infection rates, studies such as the iPARTY study are highly pertinent...
Original Article
Health-related quality of life in Singapore: Population norms for the EQ-5D-5L and EORTC QLQ-C30
Health-related quality of life (HRQOL) is a multidimensional assessment of the impact of disease and treatment on physical, psychological and social aspects of individuals’ lives.1,2 HRQOL is an important outcome measure of healthcare interventions that is increasingly used in clinical research and practice.1,3 HRQOL instruments may be generic or...
Original Article
iPARTY study: Increasing pre-exposure prophylaxis access and reach via telehealth for young men who have sex with men in Singapore 2022–2023
Human immunodeficiency virus (HIV) infection remains a significant global health challenge worldwide, with 39 million people living with HIV as of 2022.1 In Singapore, there were 209 newly diagnosed cases of HIV infections in 2023, a 3% increase from 2022.2 Although highly active antiretroviral therapy (HAART) effectively suppresses viral...
Review Article
The efficacy and safety of radiofrequency ablation in papillary thyroid carcinoma: A systematic review and meta-analysis
Malignant nodules account for 5–15% of all thyroid nodules and papillary thyroid carcinoma (PTC) accounts for 85% of that.10 Most guidelines recommend surgery as the first-line treatment for PTC.11 However, surgery does carry a risk for complications, such as hypothyroidism and recurrent laryngeal nerve damage leading to voice hoarseness.12-17...