Volume 54, Number 3
March 2025

Research explores the latest advanced role, mechanism, treatment and safety of hydroxychloroquine (HCQ) in rheumatic diseases during pregnancy and application prospects of HCQ in preeclampsia.

Illustration by Maria De-Castro

Strengthening HRQOL Assessment in Singapore: Updated Norms for EQ-5D-5L and EORTC QLQ-C30

Health-related quality of life (HRQOL) is increasingly used as an important indicator of health outcomes for measuring the impact of illness and treatment among individuals with mental or physical conditions. The EuroQol 5-dimension (EQ-5D) questionnaire is one of the most widely used generic measures for HRQOL and estimating the...

Enhancing HIV pre-exposure prophylaxis using telehealth: Insights from the iPARTY study

Human immunodeficiency virus (HIV) infections are increasing globally despite significant advancements in preventive and treatment programmes.1  This alarming trend is particularly pronounced within high-risk populations, especially among young men who have sex with men (YMSM). Given these rising infection rates, studies such as the iPARTY study are highly pertinent...

Health-related quality of life in Singapore: Population norms for the EQ-5D-5L and EORTC QLQ-C30

Health-related quality of life (HRQOL) is a multidimensional assessment of the impact of disease and treatment on physical, psychological and social aspects of individuals’ lives.1,2 HRQOL is an important outcome measure of healthcare interventions that is increasingly used in clinical research and practice.1,3 HRQOL instruments may be generic or...

iPARTY study: Increasing pre-exposure prophylaxis access and reach via telehealth for young men who have sex with men in Singapore 2022–2023

Human immunodeficiency virus (HIV) infection remains a significant global health challenge worldwide, with 39 million people living with HIV as of 2022.1 In Singapore, there were 209 newly diagnosed cases of HIV infections in 2023, a 3% increase from 2022.2 Although highly active antiretroviral therapy (HAART) effectively suppresses viral...

The efficacy and safety of radiofrequency ablation in papillary thyroid carcinoma: A systematic review and meta-analysis

Malignant nodules account for 5–15% of all thyroid nodules and papillary thyroid carcinoma (PTC) accounts for 85% of that.10 Most guidelines recommend surgery as the first-line treatment for PTC.11 However, surgery does carry a risk for complications, such as hypothyroidism and recurrent laryngeal nerve damage leading to voice hoarseness.12-17...

MOST CITED ARTICLES

Trends in fluid overload-related hospitalisations among patients with diabetes mellitus: The...

Leveraging ChatGPT to aid patient education on coronary angiogram

Risk and protective factors of mental health during the COVID-19 pandemic:...

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Variations in management strategies for stable coronary artery disease in the...

Supporting quadruple aim in primary care using artificial intelligence

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