Original Article
High-dose Therapy followed by Autologous Haematopoietic Stem Cell Transplantation in Multiple Myeloma
Multiple myeloma (MM) is a disorder in which malignant plasma cells accumulate in the bone marrow and produce an immunoglobulin, usually monoclonal IgG or...
Efficacy and Tolerability of Irinotecan in Patients with Advanced Colorectal Cancer in Singapore
Colorectal cancer is the second most commonly encountered malignancy in the developed countries; in Singapore, it is the commonest cancer. With early detection, patients...
A Twelve-year Review of Radical Cystectomies in Singapore General Hospital
Bladder carcinoma is the tenth most common cancer affecting men in Singapore. It is more common in men with an age-standardised incidence rate of...
Thyroid Dysfunction in Chronic Schizophrenia Within a State Psychiatric Hospital
Thyroid dysfunction can give rise to various psychiatric symptoms. While there is a persistent interest in the role of thyroid axis in affective disorders,...
Homocysteine, Folate and Vitamin B12 as Risk Factors for Acute Myocardial Infarction in a...
Since the beginning of the last decade, hyperhomocysteinaemia has been identified as a risk factor for acute coronary syndromes. A few large prospective studies...
The Posterior Cruciate Ligament: An Anthropometric Study in Asians and Evaluation of Safe Limits...
The posterior cruciate ligament (PCL) provides the main restraint to posterior translation of the tibia on the femur and is stronger than its anterior...
Advances in Surgical Treatment of Osteoporotic Fractures of the Spine
Osteoporosis is an important cause of fractures in the elderly. In the USA alone, at least 1.3 million fractures are attributed to osteoporosis a...
Limited Magnetic Resonance Imaging (MRI) and the Occult Hip Fracture
Worldwide, in the past decade, the application of magnetic resonance imaging (MRI) has increased tremendously in the management of musculoskeletal trauma. Not least is...
Extremity Osteosarcoma—A Southeast Asian Experience
Osteosarcoma is a highly malignant bone cancer occurring primarily in young patients. Although rare, it is still the commonest primary bone cancer seen in...
Transesophageal Echocardiography or Fluoroscopy During Port-Access Surgery?
Minimally invasive techniques are increasingly being used in cardiac surgery. In particular, coronary artery bypass grafting (CABG) and mitral valve surgery are now often...