Original Article

A randomised controlled study of canagliflozin in improving diabetic kidney disease through a podocyte...

Diabetic kidney disease (DKD) is a common and severe microvascular complication of diabetes mellitus, a leading cause of chronic kidney disease (CKD), the primary...

Endoscopic combined intrarenal surgery versus conventional percutaneous nephrolithotomy for complex renal calculi: A retrospective...

Renal calculi are among the most prevalent urological diseases worldwide, severely impairing patients’ quality of life and increasing the healthcare burden. Epidemiological data from...

Evaluation of China’s “1146” school-based myopia control programme in primary school children: A 12-month...

Myopia is a major public health concern, with global prevalence projected to approach 50% by 2050.1 In China, a large school-based study of 864,828...

Body roundness index, frailty, and prevalent self-reported stroke: An exploratory cross-sectional decomposition analysis

Stroke remains one of the most pressing public health challenges worldwide, representing a leading cause of mortality and permanent disability. In the US alone,...

Burden trends of Alzheimer’s disease and other dementias in China, 1990–2023: Sex, age, and...

Alzheimer’s disease and other dementias (ADOD) are now central to the global non-communicable disease agenda, because they combine high late-life prevalence, prolonged disability, substantial...

Trends in healthcare costs and utilisation in SingHealth 2019–2024: The effects of an ageing...

Healthcare utilisation and expenditure have risen globally, placing increasing strain on the health systemClick or tap here to enter text..1 Global health spending reached...

Association of estimated pulse wave velocity with 28-day mortality in sepsis: A MIMIC-IV study

Among patients in intensive care units (ICUs), sepsis is a major cause of mortality.1 A disease burden study showed that there were approximately 48.9...

A multicomponent control programme in nursing homes in Singapore

Nursing home (NH) residents are particularly vulnerable to infections due to advanced age, frailty, comorbidities, and the institutional nature of care. Hospital transfers for...

Prognostic value of the monocyte-to-albumin ratio in nasopharyngeal carcinoma: A retrospective cohort study

The incidence of nasopharyngeal carcinoma (NPC) is notably elevated in southern China, North Africa, and Southeast Asia (up to 35 cases per 100,000 inhabitants),...

Cognition and arthritis in adults over 50: Evidence from CHARLS, HRS, and ELSA

The world is transitioning towards older age groups, with the share of people aged 60 years and above expected to increase 2-fold by 2050.1...
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