Original Article
Healthcare cost of patients with multiple chronic diseases in Singapore public primary care setting
The rising occurrence of individuals suffering from multiple chronic diseases, namely multimorbidity, is of public health concern globally.1 The current prevalence of multimorbidity in...
Adolescent self-harm and suicide attempts: An analysis of emergency department presentations in Singapore
Within 3 years from 2019 to 2021, adolescent suicide rates in Singapore almost doubled from 5.35 to 9.14 per 100,000 population.1,2 This is against...
Investigating urinary characteristics and optimal urine white blood cell threshold in paediatric urinary tract...
Urinary tract infection (UTI) is a common diagnosis in the paediatric emergency department (ED). It accounts for an estimated 5–14% of paediatric ED visits...
Evaluating the impact of relative dose intensity on efficacy of trastuzumab deruxtecan for metastatic...
Human epidermal growth receptor 2 (HER2)-positive breast cancer is recognised as a particularly aggressive subtype, associated with a poorer prognosis and a higher risk...
Predictors of early removal of intragastric balloon due to intolerance: Insights from a multiethnic...
Obesity, affecting over 2.1 billion people globally, is an escalating health crisis with serious economic consequences.1 It is associated with multiple comorbidities including type...
Restaging of rectal cancer with hybrid positron emission tomography magnetic resonance imaging after...
Neoadjuvant chemoradiotherapy (CRT) followed by surgery is the current standard of care for locally advanced rectal cancers. Randomised trials have shown that a neoadjuvant...
Deep Vein Thrombosis after Total Knee Replacement
Western literature reports a very high incidence of deep vein thrombosis in its population especially after orthopaedic surgery. In total knee replacement without prophylaxis,...
Post-exposure prophylaxis and follow-up in children and young persons presenting with sexual assault
Sexual assault (SA) in the paediatric population is an under-recognised but significant public health burden.1,2 Effective management requires addressing the psychosocial issues involved and...
Chronic obstructive pulmonary disease 30-day readmission metric: Risk adjustment for multimorbidity and frailty
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition defined by persistent respiratory symptoms and airflow limitation.1 It is primarily caused by pathological...
Smartphone Imaging in Ophthalmology: A Comparison with Traditional Methods on the Reproducibility and Usability...
There is an increasing trend amongst medical professionals in recent years to incorporate smartphones as an informal clinical tool. The ubiquity and accessibility of...








