Original Article
Concurrent Chemoradiotherapy followed by Surgery in Locally Advanced Squamous Cell Carcinoma of the Oesophagus:...
Carcinoma of the oesophagus is a relatively uncommon malignancy in Singapore and incidence rates have been declining since 1968. A total of 506 cases...
The Prevention of Neuroma Formation by Diathermy: An Experimental Study in the Rat Common...
Neuroma formation in extremity amputations, particularly finger amputations, can be extremely disabling. There have been many methods advocated for the prevention and management of...
The Metabolic Syndrome in Hypertensive and Normotensive Subjects: The Isfahan Healthy Heart Programme
The metabolic syndrome (MS) is characterised by a clustering of metabolic risk factors and an insulin-resistant state.1 Its prevalence is high in Western, as...
Acceptance of Prophylactic Surgery and Chemoprevention of Cancer in Singapore – A Survey
The Singapore healthcare philosophy aims to establish a healthy population through preventive healthcare programmes and public health education. Public education usually emphasises the adverse...
Treatment of Benign Giant Cell Tumours of Bone in Singapore
Giant cell tumour (GCT) is a distinct neoplasm of undifferentiated cells. The exact cell of origin is unknown. The multinucleated giant cells present are...
Therapeutic Leukapheresis in Hyperleukocytic Leukaemias—The Experience of a Tertiary Institution in Singapore
Hyperleukocytic leukaemia is conventionally defined as leukaemia with an initial white blood cell (WBC) count or blast count greater than 100,000/mm3 . 1 It...
Laparoscopic-assisted Colon and Rectal Surgery – Lessons Learnt from Early Experience
Great strides in laparoscopic surgical techniques have been progressively made throughout the various surgical subspecialties. More procedures can be performed laparoscopically today than when...
A Two-stage Approach Identifies a Q344X Mutation in the Rhodopsin Gene of a Chinese...
Retinitis pigmentosa (RP, MIM#26800) is a group of hereditary retinal diseases that feature progressive photoreceptor degeneration, eventually leading to partial or complete blindness. It...
Narcolepsy in Singapore: Is it an Elusive Disease?
Narcolepsy is a sleep disorder characterised by excessive sleepiness, disturbed nocturnal sleep and abnormal rapid eye movement (REM) sleep-related events, such as cataplexy, hypnogogic/hypnopompic...
Measurable Predictive Factors for Progression to AIDS among HIV-infected Patients in Singapore
The first case of human immunodeficiency virus (HIV) infection was detected in Singapore on 16May 1985. The number of newly diagnosed HIV/acquired immuno-deficiency virus...