Original Article
Mutation Screening in KCNQ1, HERG, KCNE1, KCNE2 and SCN5A Genes in a Long QT...
Long QT syndrome (LQTS), a form of life-threatening cardiac arrhythmia, is a rare but significant clinical disorder, with a prevalence of 1 in 10,000...
Intracranial Aneurysm Detection with 3T Magnetic Resonance Angiography
The recent advent of 3 Tesla (T) very high field magnetic resonance (MR) systems into clinical practice has enabled a variety of exciting developments...
High Coverage of Influenza Vaccination Among Healthcare Workers Can Be Achieved During Heightened Awareness...
Experts have warned that Asia may be the next influenza pandemic epicentre.1 In order to reduce the risks of genetic shifts in the avian...
Predictors of Vancomycin-resistant Enterococcus (VRE) Carriage in the First Major VRE Outbreak in Singapore
Vancomycin-resistant enterococci (VRE) have emerged as one of the most challenging nosocomial threats in the past decade globally.1,2 Although antibiotic exposure may facilitate VRE...
Improvements in Quality of Care Resulting From a Formal Multidisciplinary Tumour Clinic in the...
Multidisciplinary care has now been established as the optimal management principle for the majority of malignancies.1,2 However, the model of multidisciplinary care, specifically the...
Salvage Chemotherapy in Progressive High-grade Astrocytoma
High-grade astrocytoma includes glioblastoma multiforme (GBM) (World Health Organization grade 4) and anaplastic astrocytoma (AA) (WHO grade 3). These are the more common gliomas...
Improved Median Survival for Glioblastoma Multiforme Following Introduction of Adjuvant Temozolomide Chemotherapy
WHO grade IV glioma or glioblastoma multiforme (GBM) is a highly aggressive primary brain tumour that accounts for 50% to 60% of intracranial glioma.1...
Optimising Radiation Therapy Techniques for Tumours of the Central Nervous System
Tumours of the central nervous system (CNS) are a diverse group of pathologies with varying natural histories and outcomes. The presence of adjacent sensitive...
Awake Craniotomy Under Local Anaesthesia and Monitored Conscious Sedation for Resection of Brain Tumours...
The aims of surgical management in the resection of brain tumours are to obtain an accurate histological diagnosis, achieve maximal resection with minimal morbidity,...
Anaesthetic Management of Awake Craniotomy for Tumour Resection
Historically, surgery for intractable epilepsy was performed with the patient awake for at least some part of the procedure to facilitate cortical mapping and...