Volume 48, Number 4
April 2019

Reproduced with permission from: Anonymous

“Education is the most powerful weapon which you can use to change the world.”

Nelson Mandela (1918-2013)
South African statesman

Stem Cell Replacement Therapies in Parkinson’s Disease

World Parkinson’s Disease Day—which falls on 11 April—commemorates the birthday of the late physician and geologist, James Parkinson. All around the world, efforts are under way to increase public awareness of the condition first described by Parkinson over 200 years ago. Over the past 2 decades, Parkinson’s disease (PD)...

Validating a Standardised Approach in Administration of the Clinical Frailty Scale in Hospitalised Older Adults

Singapore is ageing at an exponential rate. Commensurate with the worldwide trend of population ageing, 13% of residents were aged 65 years and older in 2017 with a life expectancy of 83.1 years.1 By 2030, the aged population is projected to constitute approximately 25% of its total population with...

Electronic Bicycles and Scooters: Convenience at the Expense of Danger?

Electronic bicycles and scooters—or personal mobility devices (PMDs)—are becoming popular means of commute given their convenience, low cost and ease in obtaining regulatory approval. They have also been successfully marketed as a fun and environment-friendly way to travel. However, the recent surge in PMD-related accidents is cause for concern....

First Percutaneous Tricuspid Valve Repair with MitraClip Device in Singapore

Treatment of patients who have severe mitral regurgitation (MR) and tricuspid regurgitation (TR) is surgical repair or replacement. However, it becomes a therapeutic challenge in patients who are at prohibitive surgical risk. In such patients, percutaneous edge-to-edge repair of mitral valve with the MitraClip system (Abbott Vascular, Santa Clara,...

HLA-B*5701 Genotyping for Abacavir Prescription: Re-Examination of its Cost-Effectiveness in Singapore

Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI) that is used to control disease progression of human immunodeficiency viruses (HIV). It reduces the morbidity and mortality of HIV infections.1 A serious side effect of abacavir is hypersensitivity reaction (HSR) which usually begins within 6 weeks of starting treatment and...

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